✨ Under the sky of research… 🌙🔬An evening at the Music Park in Taranto, where science and art met. 🎶#ERN2024
#ERN2024 NightOfResearchers #Taranto #polodellamusica
PLATFORM REVOLUTIONIZING DISEASE DETECTION
A binary sensor revolutionizing non-invasive screening
The ERC Starting grantNoOne: A binary sensor with single-molecule digit to discriminate biofluids enclosing zero or at least one biomarker, founded by European Research Council Executive Agency for 5 years (GA 101040383)
NoOne project aims at conceiving, engineering, fabricating and validating a ground-breaking platform based on a single-molecule binary bioelectronic sensor, capable to reliably discriminate biofluid samples enclosing zero biomarkers from those containing just one. The technology can be used for ultimate binary sensing of both proteins/peptides and genomic markers to enable the reliable screening of diseases such as cancer as well as viral and bacterial infections.
The NoOne platform is endowed with a machine-learning / artificial intelligence algorithm, to ensure an incidence of false positives and false negatives below 1-5%.
THE PRINCIPAL INVESTIGATOR (PI)
Dr. Eleonora Macchia, Class of ’90, is a tenure-track Assistant Professor in Analytical Chemistry at the Department of Pharmaceutical Sciences, University of Bari, and the Head of Research at Åbo Akademi University. Moreover, she is the Scientific Responsible for the University of Bari node of the Regional Center for Innovation in Single-molecule Digital Assay (www.singlemolecule.center ), serving as Biostatistician in the Clinical Trial for In vitro diagnostic (IVD) device non-interventional performance study on left-over specimens.
Her research interest are focused on the development of ultrasenstitive biosensing platform, multivariate data processing, process monitoring and Design of Experiments. She has served as a Senior Researcher and Principal Investigator of the ProSiT project, funded by the Academy of Finland Research Council (GA#332106). Since March 2019, she has held the position of Project Researcher at Åbo Akademi University within the framework of the H2020 project SiMBiT (GA#824946). Prior to this, she was a Postdoctoral Fellow at the University of Bari. Dr. Macchia earned her Ph.D. in Chemical Sciences with honors (summa cum laude) in 2018 from the University of Bari and her Master’s degree in Physics with honors (110/110 cum laude) in 2014 from the same institution.
She has been honored with 11 scientific awards and was selected as a Top 10 candidate for the XVII Edition of the “L’Oréal Italia Per le Donne e la Scienza” award. At the age of 33, she has already authored 67 publications in major international journals since 2013, accumulating a total of 1,425 citations and achieving an h-index of 20. Dr. Macchia is also a co-inventor of two patents. Beyond her research accomplishments, she is deeply committed to serving as a role model for young women scientists, actively promoting women’s representation in Science and Engineering. She initiates programs aimed at encouraging more girls to pursue studies in these fields and strives to raise the visibility of women working in STEM.
7 years married and our first anniversary in the new house! 🏡💕 Celebrated with a homemade dinner and our little girl by our side. Feeling so lucky and grateful for this life together. Here’s to many more! 🥂❤️
#Anniversary #7Years #NewHome #Familylove
✨ Sotto il cielo della ricerca... 🌙🔬
Una serata al Parco della Musica di Taranto, dove scienza e arte si sono incontrate. 🎶
@ERC_Research #ERN2024
#NotteDeiRicercatori #Taranto #polodellamusica
The Regional Innovation Center for Single Molecule Digital Assay, represented by President Luisa Torsi and Scientific Directors Eleonora Macchia and Fabrizio Torricelli, took part in Orbitaly in Bologna. #orbitaly @MacchiaEle @FabTorricelli
#ERN2024 NightOfResearchers #Taranto #polodellamusica
The Regional Innovation Center for Single Molecule Digital Assay, represented by President Luisa Torsi and Scientific Directors Eleonora Macchia and Fabrizio Torricelli, took part in
The whole team congratulates Prof. Torsi, who was awarded the prestigious ‘Lifetime Achievement Award’ by the Division of Analytical Chemistry!
We thanks all the invited speakers, Marco Rolandi, Wei Gao, Manuela Ciocca and Adrica Kyndiah, and all the speakers! Luisa Torsi Eleonora Macchia Paolo Bollella
I am incredibly grateful to everyone who has supported me along this journey. Special thanks to my mentor, Prof. Luisa Torsi, for her invaluable guidance
The NoOne project aims to develop, design, implement, and validate an innovative platform based on a single-molecule binary bioelectronic sensor that can reliably discriminate biofluid samples lacking biomarkers from those containing at least one
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